Intelligent MRI Analysis for Parkinson’s Disease Detection

Authors

  • R. Indhumathi Department of AI/ML, Department of Computer Science, Idhaya College for Women, Kumbakonam, India
  • Alaa A. ELnazer Department of Marketing, College of Business, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia
  • Sharvari R. Shukla Symbiosis Statistical Institute, Symbiosis International (Deemed University), Pune, India
  • Showkat A. Da Department of Computer Science and Engineering, GITAM University Bangalore Campus -561203, India
  • Hela Hakim Researcher Associated with the MIRACL Laboratory, University of Sfax, Tunisia-3029
  • A. Vijaya Mahendra Varman Department of Artificial Intelligence and Data Science, Panimalar Engineering College-600 123, Chennai, India
  • Tanvir Habib Sardar Department of CSE, School of Engineering, Dayananda Sagar University, Bengaluru–562112, India
  • Aafaq A. Rather Symbiosis Statistical Institute, Symbiosis International (Deemed University), Pune, India

DOI:

https://doi.org/10.6000/

Keywords:

MRI Classification, Computer Aided Diagnosis, SIFT, LBP, KNN

Abstract

This study presents a practical approach for classifying Magnetic Resonance Imaging (MRI) scans to distinguish between normal subjects and those affected by Parkinson’s disease (PD). PD is a progressive brain disorder marked by dopamine deficiency, and lacks reliable diagnostic methods for early detection. To overcome this challenge, we employed Scale-Invariant Feature Transform (SIFT) and Local Binary Pattern (LBP) in designing a Computer-Aided Diagnostic (CAD) System. The extracted features are classified using K-Nearest Neighbour (KNN) and Decision Tree algorithms. Experimental results show that LBP features classified through the Decision Tree achieved the highest accuracy of 97.41%, demonstrating the efficiency of the proposed method in achieving early and accurate detection of PD. 

References

Mozhdehfarahbakhsh A, Chitsazian S, Chakrabati P, Chakrabarti T, Kateb B, Nami M. An MRI-based Deep Learning Model to predict Parkinson’s Disease Stages. Medline 2021. https://doi.org/10.1101/2021.02.19.21252081[2]Pereira CR, Pereira DR, Silva FA, Hook C. A Step Towards the Automated Diagnosis of Parkinson’s Disease: Analyzing Handwriting Movements. IEEE 28 International Symposium on Computer-Based Medical Systems 2015.https://doi.org/10.1109/CBMS.2015.34[3]Challa KNR, Pagolu VS, Panda G. An Improved Approach for Prediction of Parkinson’s Disease using Machine Learning. International Conference on Signal Processing, Communication, Power and Embedded System 2016.https://doi.org/10.1109/SCOPES.2016.7955679[4]Shah PM, Zeb A, Shafi U, Zaidi SFA, Shah MA. Detection of Parkinson’s Disease in Brain MRI using Convolutional Neural Network. Proceedings of the 24th International Conference on Automation &Computing, Newcastle University 2018. https://doi.org/10.23919/IConAC.2018.8749023[5]Senturk ZK. Early Diagnosis of Parkinson’s Disease using Learning Algorithms. Medical Hypotheses 2020; 138.https://doi.org/10.1016/j.mehy.2020.109603[6]Anitha S. Improved Classification Accuracy for Diagnosing the Early Stage of Parkinson’s Disease using Alpha Stable Distribution. The Institution of Electronics and Telecommunication Engineers 2021. https://doi.org/10.1080/03772063.2021.1910580[7]Adel E, Elmogy M, Elbakry H. Image stitching based on feature extraction techniques: a survey. International Journal of Computer Applications 2014; 99(6): 1-8.https://doi.org/10.5120/17374-7818[8]Lowe DG. Distinctive image features from scale invariant key points. International Journal of Computer Vision 2004; 60(2): 91-110. https://doi.org/10.1023/B:VISI.0000029664.99615.94[9]Chiu LC, Chang TS, Chen JY, Chang NYC. Fast SIFT designs for real-time visual feature extraction. IEEE Transactions on Image Processing 2013; 22(8): 3158-3167.https://doi.org/10.1109/TIP.2013.2259841[10]Fradi H, Dugelay JL. A new multiclass SVM algorithm and its application to crowd density analysis using LBP features. International Conference on Image Processing IEEE 2013; pp. 4554-4558.https://doi.org/10.1109/ICIP.2013.6738938[11]Vasanawala SS, Nguyen KL, Hope MD, Bridges MD, Hope TA, Reeder SB, Bashir MR. Safety and technique of Ferumoxytol administration for MRI. Magnetic Resonance in Medicine 2016; 75(5): 2107-2111.https://doi.org/10.1002/mrm.26151[12]Agrawal R. K-Nearest Neighbor for Uncertain Data. International Journal of Computer Applications 2014; 105(11): 13-16.[13]Dar SA, et al. Improving Alzheimer’s Disease Detection with Transfer Learning. Int J Stat Med Res 2025; 14: 403-415. https://doi.org/10.6000/1929-6029.2025.14.39[14]Dar SA, Palanivel S, Geetha MK, Balasubramanian M. Mouth Image Based Person Authentication Using DWLSTM and GRU. Inf Sci Lett 2022; 11(3): 853-862. https://doi.org/10.18576/isl/110317[15]Dar SA, Palanivel S. Performance Evaluation of Convolutional Neural Networks (CNNs) And VGG on Real Time Face Recognition System. Adv Sci Technol Eng Syst J 2021; 6(2): 956-964. https://doi.org/10.25046/aj0602109[16]Dar SA, Palanivel S. Real Time Face Authentication System Using Stacked Deep Auto Encoder for Facial Reconstruction. Int J Thin Film Sci Technol 2022; 11(1): 73-82. https://doi.org/10.18576/ijtfst/110109[17]Dar SA, PS. Real-Time Face Authentication Using Denoised Autoencoder (DAE) for Mobile Devices 2022; 21(6): 163-176. https://doi.org/10.4018/978-1-7998-9795-8.ch011[18]Ayadi W, et al. AI-Powered CNN Model for Automated Lung Cancer Diagnosis in Medical Imaging. Int J Stat Med Res 2025; 14: 616-625.https://doi.org/10.6000/1929-6029.2025.14.58[19]Ibrahim H, Mahmoud M, Ahmad M, Mandouh R. Different Approaches for Outlier Detection in Life Testing Scenarios. Computational Journal of Mathematical and Statistical Sciences 2024; 3(1): 203-227. https://doi.org/10.21608/cjmss.2024.254148.1033[20]Onyekwere C, Nwankwo C, Obulezi O, Ezeilo C. The feature-value paradox: Unsupervised discovery of strategic archetypes in the smartphone market using machine learning. Journal of Artificial Intelligence in Engineering Practice 2025; 2(2): 65-72. https://doi.org/10.21608/jaiep.2025.420689.1024[21]Raihen MN, Hossain MI, Chellamuthu V. Predicting clinical outcomes in liver cirrhosis using machine learning and data balancing technique. Computational Journal of Mathematical and Statistical Sciences 2025; 4(2): 664-696. https://doi.org/10.21608/cjmss.2025.397747.1213[22]Shalaby Y, Embark A. A predictive model for climate change using advanced machine learning algorithms in Egypt. Journal of Artificial Intelligence in Engineering Practice 2025; 2(2): 1-21. https://doi.org/10.21608/jaiep.2025.415474.1020[23]Nnaekwe K, Ani E, Obieke V, Okechukwu C, Usman A, Othman M. Forecasting seasonal rainfall with time series, machine learning and deep learning. Innovation in Computer and Data Sciences 2025; 1(1): 51-65. https://doi.org/10.64389/icds.2025.01127[24]Almetwally EM, Elbatal I, Elgarhy M, Kamel AR. Implications of machine learning techniques for prediction of motor health disorders in Saudi Arabia, Alexandria Engineering Journal 2025; 127: 1193-1208.https://doi.org/10.1016/j.aej.2025.07.015

Downloads

Published

2025-12-01

Issue

Section

General Articles

How to Cite

Intelligent MRI Analysis for Parkinson’s Disease Detection. (2025). International Journal of Statistics in Medical Research, 14, 745-754. https://doi.org/10.6000/

Similar Articles

1-10 of 86

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)