Cardiovascular Disease and Mental Health in Intellectual Disabilities: A Vicious Cycle of Risk and Care Gaps
DOI:
https://doi.org/10.6000/2292-2598.2025.13.02.3Keywords:
Cardiovascular disease, intellectual disability, mental health, depression, anxietyAbstract
Background: Cardiovascular diseases (CVDs) are the primary reason for demise and disability worldwide, with a particularly severe problem in low- and middle-income nations. Among individuals with intellectual disabilities (ID), the coexistence of cognitive impairments, mental health conditions, and barriers to medical care significantly increases health risks.
Objective: This review discovers the bidirectional connection between cardiovascular disease and mental health disorders in individuals with ID. It aims to classify risk factors, examine care disparities, and evaluate the need for targeted interventions.
Methods: A descriptive review methodology was employed. A total of 1,182 articles were initially retrieved from PubMed, Scopus, and PsycINFO using a focused keyword strategy encompassing CVD, mental health, and intellectual disability. After applying inclusion criteria centered on disability relevance and peer-reviewed content, 914 articles were shortlisted. From these, 173 studies were selected based on quality and contextual suitability.
Results: The review identified a consistent pattern of underrepresentation of individuals with ID in cardiovascular and psychiatric research despite their increased rates of congenital heart defects, lifestyle-related risk factors, and untreated mental health issues. Diagnostic overshadowing, resource constraints for caregivers, and a lack of appropriately adapted therapies further aggravate their vulnerability. Evidence suggests that caregiver-supported and community-based interventions, when customized for this population, can improve health outcomes.
Conclusion: The interplay between cardiovascular disease and mental health in people with ID constitutes a complex clinical and public health challenge. A disability-sensitive research and care framework is urgently needed. Future approaches should focus on early screening, tailored interventions, integrated care models, and inclusive health policies to adequately support this marginalized population.
References
Saxena V, Kandpal SD, Goel D, Bansal S. SP3-16 Prevalence of risk factors of non-communicable diseases in rural population of India. J Epidemiol Community Health [Internet] 2011; 65(Suppl 1): A413.
News-Medical. Young adults with depression and poor mental health are more likely to develop cardiovascular disease [Internet] 2023 Jan 30 [cited 2023 Jan 30]. Available from: https://www.news-medical.net/news/20230130/Young-adults-with-depression-and-poor-mental-health-more-likely-to-develop-cardiovascular-disease.aspx
Coviello K. Challenges and Opportunities in Medicaid Value-Based Care - CWH Advisors [Internet]. CWH Advisors; 2024 Oct 31 [cited 2024 Oct 31]. Available from: https://cwhadvisors.com/insights/challenges-and-opportunities-in-medicaid-value-based-care/
Rojer. Phil Collins' Health Struggles: A journey through music and personal challenges - Pro News Hub Feed [Internet]. Pro News Hub Feed; 2024 Sep 25 [cited 2024 Sep 25]. Available from: https://pronewshubfeed.com/phil-collins-health-struggles-a-journey-through-music-and-personal-challenges/
Boucher J. Améliorer sa santé avec les soins cardiovasculaires [Internet]. Laval Cardiovascular Evaluation Center; 2024 Aug 26 [cited 2024 Feb 21]. Available from: https://www.centrecardiolaval.com/en/2024/02/21/improving-health-with-cardiovascular-care/
IGAKU. July 27, 2024 - IGAKU [Internet] 2024 Jul 27 [cited 2024 Jul 27].
Tobler H. Mental health care cuts cardiac ED visits [Internet]. Medical Republic; 2024 Apr 15 [cited 2024 Apr 15]. Available from: https://www.medicalrepublic.com.au/mental-health-care-cuts-cardiac-ed-visits/106728
Pixeladmin. Navigating mental health support in private school settings [Internet]. Orlando Private Schools; 2024 Feb 28 [cited 2024 Feb 28]. Available from: https://orlandoprivateschools.com/navigating-mental-health-support-in-private-school-settings/
Jorgensen MB. Highlights from the Nordic Journal of Psychiatry (June - October of 2023) [Internet]. Nordic Psychiatrist; 2023 Nov 5 [cited 2023 Nov 5]. Available from: https://www.thenordicpsychiatrist.com/post/highlights-from-the-nordic-journal-of-psychiatry-june-october-of-2023
Api S. Mind and Society: Mental Health Disorders Shaping Social Thinking [Internet]. SocialStar; 2023 Aug 2 [cited 2023 Aug 2]. Available from: https://officialsocialstar.com/blogs/ blog/mind-and-society-mental-health-disorders-shaping-social-thinking
Gacor G. Gambling and depression - kellygreenbb.com [Internet] 2023 Jul 31 [cited 2023 Jul 31]. Available from: https://kellygreenbb.com/gambling-and-depression/
Vishu. Mental Health awareness [Internet]. Ganga News Today; 2023 Jul 19 [cited 2023 Jul 19]. Available from: https://www.ganganews.com/health/mental-health-awareness/
Grandlacsmedjour. (2023, February 25). [36] reported that woman patients have higher anti-Ro levels than males – kinase inhibitor screen identifies Therapy and the Risk for Depression. https://grandlacs-med-journal.com/2023/02/25/ 36-reported-that-woman-patients-have-higher-anti-ro-levels-than-males/
Osborn BM. Sleep-Wake Patterns Archives - Health care reform [Internet]. Health Care Reform; 2023 Jan 3 [cited 2023 Jan 3]. Available from: https://www.healthcarereformmagazine.com/tag/sleep-wake-patterns/
Dastmalchi LN. Mental health was seen as a possible new risk factor for heart disease: Why women are more affected [Internet]. ABC News; 2021 Feb 18 [cited 2021 Feb 18]. Available from: https://abcnews.go.com/GMA/Wellness/ mental-health-risk-factor-heart-disease-women-affected/story?id=75926151
Gupta R, Wood DA. Primary prevention of ischaemic heart disease: Populations, individuals, and health professionals. Lancet 2019; 394(10199): 685-96.
Zambrano J, Celano CM, Januzzi JL, Massey CN, Chung WJ, Millstein RA, et al. Psychiatric and psychological interventions for depression in patients with heart disease: a scoping review. J Am Heart Assoc 2020; 9(22): e018686.
Zhou Y, Zhu X, Shi J, Yuan G, Yao Z, Chu Y, et al. Coronary heart disease and depression or anxiety: a bibliometric analysis. Front Psychol [Internet] 2021; 12: 669000.
Zambrano J, Celano CM, Januzzi JL, Massey CN, Chung W, Millstein RA, et al. Psychiatric and psychological interventions for depression in patients with heart disease: a scoping review. J Am Heart Assoc 2020; 9(22).
Susinski S, Bouchard K, Stragapede E, Dozois S, Sterling E, Tulloch H. Psychological interventions targeting mental health and stress among females with cardiac disease: a scoping review. Can J Physiol Pharmacol 2024; 102(10): 607-19.
Golubnitschaja O. Gender-related differences in CVD and deficits in female healthcare. EPMA J 2014; 5(S1).
Zaidi Z, de Ferranti SD. Prevalence of high blood pressure among youth in India and association with future cardiovascular disease. JAMA Netw Open [Internet] 2022; 5(10): e2238020.
Yang J, Lo K, Yang A. Trends in urinary and blood cadmium levels in U.S. adults with or without comorbidities, 1999-2018. Nutrients [Internet] 2022; 14(4): 802.
Yan X, Ma H, Liu S-S, Gong Q. Correlation among anxiety and depression, fear of disease progression, and social support in coronary heart disease. World J Psychiatry [Internet] 2024; 14(11): 1708-17.
Xu Y, Ma H, Liu S, Gong Q. Correlation among anxiety and depression, fear of disease progression, and social support in coronary heart disease. World J Psychiatry [Internet] 2024; 14(11): 1708-17.
Xu L, Zhai X, Shi D, Zhang Y. Depression and coronary heart disease: mechanisms, interventions, and treatments. Front Psychiatry [Internet] 2024; 13: 1328048.
Business Group on Health. Women's health guide: preventive health [Internet]. Available from: https://businessgrouphealth.org/en/resources/womens-health-guide-preventive-health
Wheeler AJ, Harrison J, Homes Z. Cardiovascular risk assessment and management in mental health clients: perceptions of mental health and general practitioners in New Zealand. J Prim Health Care [Internet] 2009; 1(1): 11-9.
Nutrition Facts. What are the symptoms of atherosclerosis? [Internet]. [cited 2024]. Available from: https://www.nutritionfact.in/faqs/what-are-the-symptoms-of-atherosclerosis?amp=1
Wetzel S, Geldsetzer P, Mani SS, Singh K, Ali MK, Prabhakaran D, et al. Changing socioeconomic and geographic gradients in cardiovascular disease risk factors in India - evidence from nationally representative household surveys. medRxiv [Preprint] 2022.
Watkins DA, Nugent R, Verguet S. Extended cost-effectiveness analyses of cardiovascular risk factor reduction policies. Int Bank Reconstr Dev World Bank [Internet] 2017 [cited 2024].
Warrior Academy Blog. Disorders [Internet]. [cited 2024]. Available from: https://blog.warrioracademy.club/tag/ disorders
Wang J, Li T, Gu Y, Su B, Wang H, Lai C, et al. The value of anxiety and depression in predicting physical function and major adverse cardiovascular events in patients with acute coronary syndrome. J Thorac Dis 2024; 16(10): 6849-62.
Wajanga BMK, Kim CY, Peck RN, Bartlett J, Mabula D, Juma A, et al. Is lack of health insurance a predictor of worsening heart failure among adult patients attending referral hospitals in Northwestern Tanzania? PLoS One 2022; 17(3): e0264352.
Vu LTH. Multilevel determinants of children's health outcomes [Internet] 2005 [cited 2025 May 21]. Available from: https://core.ac.uk/download/226162579.pdf
Vasant RS, Rao LKM, Rao N. A cross-sectional study on demographic factors affecting low birth weight. Int J Community Med Public Health 2019; 6(11): 4896.
Vasan SK, Antonisamy B, Gowri M, Selliah HY, Geethanjali FS, Jebasingh FS, et al. Prevalence, incidence, and predictors of cardiovascular risk factors: longitudinal data from rural and urban South India and comparison with global data. BMJ Open Diabetes Res Care 2020; 8(1): e001782.
Van Kempen BJH. Evaluating strategies for the primary prevention of cardiovascular disease [Internet]. Rotterdam: Erasmus University; 2015 [cited 2025 May 21]. Available from: https://core.ac.uk/download/43308007.pdf
Daily Topic Hub. Unveiling cardiovascular disease: prevalence, prevention, and patients' perspective [Internet]. [cited 2025 May 21]. Available from: https://dailytopichub.com/unveiling-cardiovascular-disease-prevalence-prevention-and-patients-perspective/
Thompson DR, Pedersen SS. Psychosocial assessment and psychological interventions following a cardiac event. Heart 2023; heartjnl-321607.
Thomas MDP. Three essays on the impact of welfare policies [Internet] 2016 [cited 2025 May 21].
ACLS. The interplay between mental health and cardiovascular disease [Internet]. [cited 2025 May 21]. Available from: https://acls.com/articles/exploring-the-interplay-between-mental-health-and-cardiovascular-disease/
Renew Counseling. The impact of moving on mental health: navigating transitions with resilience [Internet]. [cited 2025 May 21]. Available from: https://renew-counseling.org/the-impact-of-moving-on-mental-health-navigating-transitions-with-resilience/
Thakur J. Key recommendations of high-level expert group report on universal health coverage for India. PubMed 2011.
Tettegah E, Hormenu T, Ebu-Enyan NI. Risk factors associated with anaemia among pregnant women in the Adaklu District, Ghana. Front Glob Womens Health 2024; 4: 1140867.
Tabernero C, Gutiérrez-Domingo T, Vecchione M, Cuadrado E, Castillo-Mayén R, Rubio S, et al. Correction: A longitudinal study on perceived health in cardiovascular patients: the role of conscientiousness, subjective wellbeing, and cardiac self-efficacy. PLoS One 2020; 15(2): e0229582.
Sun J, Qiao Y, Zhao M, Magnussen CG, Xi B. Global, regional, and national burden of cardiovascular diseases in youths and young adults aged 15-39 years in 204 countries/territories, 1990-2019: a systematic analysis. BMC Med 2023; 21(1).
Sui X, Liu T, Liang Y, Zhang B. Psychiatric disorders and cardiovascular diseases: a Mendelian randomization study. Heliyon 2023; 9: e20754.
Rijal A, Adhikari TB, Khan JAM, Berg-Beckhoff G. The economic impact of non-communicable diseases among households in South Asia and their coping strategy: a systematic review. PLoS One 2018; 13(11): 1-23.
Environmental Protection. Study: cities are ecosystems in their own right [Internet] 2008 Feb 22 [cited 2025 May 21]. Available from: https://eponline.com/articles/2008/02/22/ study-cities-are-ecosystems--in-their-own-right.aspx
Health Hit. Study suggests treating anxiety and depression significantly reduces ER visits and rehospitalizations among heart disease patients [Internet]. [cited 2025 May 21]. Available from: https://healthit.my.id/study-suggests-treating-anxiety-and-depression-significantly-reduces-er-visits-and-rehospitalizations-among-heart-disease-patients.html
Strohmer B, Reiter R, Hölzl B, Paulweber B. Lack of association of the Gly972Arg mutation of the insulin receptor substrate‐1 gene with coronary artery disease in the Austrian population. J Intern Med 2003; 255(1): 146-7.
Stevens B, Pezzullo L, Verdian L, Tomlinson J, George AM, Bacal F. The economic burden of heart conditions in Brazil [Internet] 2018.
Stevee S. The impact of classroom-based psychological education on student well-being. J Educ Verkenning 2023: 008-13. Available from: https://core.ac.uk/download/ 599655925.pdf
Steptoe A, Wardle J, Marmot M. Positive affect and health-related neuroendocrine, cardiovascular, and inflammatory processes. Proc Natl Acad Sci USA 2005; 102(18): 6508-12.
Sreenivasan J, Khan MS, Khan SU, Hooda U, Aronow WS, Panza JA, et al. Mental health disorders among patients with acute myocardial infarction in the United States. Am J Prev Cardiol 2020; 5: 100133.
Sobolewska-Nowak J, Wachowska K, Nowak A, Orzechowska A, Szulc A, Płaza O, et al. Exploring the heart-mind connection: unraveling the shared pathways between depression and cardiovascular diseases. Biomedicines 2023; 11(7): 1903.
Heart Disease Facts. Sleep deprivation in midlife increases women's risk of cardiovascular disease [Internet] 2024 Feb 16 [cited 2025 May 21]. Available from: https://heartdiseasefacts.com/index.php/2024/02/16/sleep-deprivation-in-midlife-increases-womens-risk-of-cardiovascular-disease/
Ski CF, Taylor RS, McGuigan K, Long L, Lambert JD, Richards SH, et al. Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure, or atrial fibrillation. Cochrane Database Syst Rev 2024; 2024(5).
Azad S, Islam AKMM, Haque MM, Sayami LA, Ahmed F, Rahman H. Clinical and sociodemographic profile and echo diagnosis pattern at NICVD. Sch J Appl Med Sci 2024; 12(12): 1735-41.
Shroufi A, Chowdhury R, Anchala R, Stevens S, Blanco P, Han T, et al. Cost-effective interventions for the prevention of cardiovascular disease in low and middle-income countries: a systematic review. BMC Public Health 2013; 13(1): 285.
Shivashankar R, Singh K, Kondal D, Gupta R, Perel P, Kapoor D, et al. Cardiovascular health in India - a report card from three urban and rural surveys of 22,144 adults. Glob Heart 2022; 17(1).
Sher Y, Lolak S, Maldonado JR. The impact of depression on heart disease. Curr Psychiatry Rep 2010; 12(3): 255-64.
Shapiro MD, Fazio S. From lipids to inflammation. Circ Res 2016; 118(4): 732-49.
Shakya S, Karmarcharya B, Koju R, Stunes A, Mosti M, Gustafsson M, et al. Diabetes prevalence and associated risk factors among women in a rural district of Nepal using HbA1c as a diagnostic tool: a population-based study. Int J Environ Res Public Health 2022; 19(12): 7011.
Schürr A, Elbel J, Hieronimi A, Auer I, Coenen M, Böse-O’Reilly S. Mental health in adolescents after experiencing a flood event in Bavaria, Germany—a qualitative interview study. Front Public Health 2023; 11.
Schulz AJ, House JS, Israel BA, Mentz G, Dvonch JT, Miranda PY, et al. Relational pathways between socioeconomic position and cardiovascular risk in a multiethnic urban sample. J Epidemiol Community Health 2008; 62(7): 638-46.
Sawaya H. Negative and positive attention bias in anhedonia and anxious arousal [Internet] 2021 [cited 2025 May 21]. Available from: https://core.ac.uk/download/483349917.pdf
Sanderson JE, Mayosi B, Yusuf S, Reddy S, Hu S, Chen Z, et al. Global burden of cardiovascular disease. Heart 2007; 93(10): 1175.
Sanchís-Gomar F, Lippi G. The forgotten connection: Mental health and cardiovascular disease. Heart Mind 2024.
Saeed A, Dabhadkar K, Virani SS, Jones PH, Ballantyne CM, Nambi V. Cardiovascular disease prevention: training opportunities, the challenges, and future directions. Curr Atheroscler Rep 2018; 20(7).
Roy M, Protity AT, Das S, Dhar P. Prevalence and major risk factors of non-communicable diseases: a machine learning based cross-sectional study. EUREKA Health Sci 2023; 3: 28-45.
Rashid S, Qureshi AG, Noor TA, Yaseen K, Sheikh MAA, Malik M, et al. Anxiety and depression in heart failure: an updated review. Curr Probl Cardiol 2023; 48(11): 101987.
Rarau P, Gouda H, Phuanukoonon S, Bullen C, Scragg R, McPake B, et al. Socio-economic status and behavioural and cardiovascular risk factors in Papua New Guinea: a cross-sectional survey. PLoS One 2019; 14(1): e0211068.
Rao KD, Bhatnagar A, Murphy A. Socio-economic inequalities in the financing of cardiovascular and diabetes inpatient treatment in India. Indian J Med Res 2011; 133(1): 57-63.
Praveen D, Peiris D, MacMahon S, Mogulluru K, Raghu A, Rodgers A, et al. Cardiovascular disease risk and comparison of different strategies for blood pressure management in rural India. BMC Public Health 2018; 18(1).
Prabhakaran D, Jaacks LM. Reflections from India on scaling up risk factor control for cardiovascular diseases to reach 1 billion adults. Circulation 2018; 139(1): 4-6.
Popandsly A. ILIADE: Impact d’une stratégie ciblée sur les patients à faible niveau de littéra [Internet]. [cited 2025 May 21]. Available from: https://www.reshapelab.fr/portfolio-projets/methodology/iliade-impact-d-une-strategie-ciblee-365.html
Polcwiartek C, O’Gallagher K, Friedman DJ, Correll C, Solmi M, Jensen SE, et al. Severe mental illness: cardiovascular risk assessment and management. Eur Heart J 2024; 45: 987-97.
Pogosova N, Kotseva K, De Bacquer D, von Känel R, De Smedt D, Bruthans J, et al. Psychosocial risk factors about other cardiovascular risk factors in coronary heart disease: results from the EUROASPIRE IV survey. Eur J Prev Cardiol 2017; 24(13): 1371-80.
Phelan SM, Salinas M, Pankey T, Cummings G, Allen JS, Waniger A, et al. Perspectives on stigma in integrated behavioral health. Ann Fam Med 2023; 21(Suppl 2): S56-60.
Peñuela-O'Brien E, Wan M, Edge D, Berry K. Mental healthcare for migrants and refugees in Europe: A qualitative systematic review. Transcult Psychiatry 2022; 60: 176-98.
Peltzer S, Müller H, Köstler U, Schulz-Nieswandt F, Jessen F, Albus C. Detection and treatment of mental disorders in patients with coronary heart disease (MenDis-CHD): A cross-sectional study. PLoS One 2020; 15(12): e0243800.
Pedersen SS, Van Domburg RT, Theuns DAMJ, Jordaens L, Erdman RAM. Type D personality and anxiety/depression in ICD patients and partners. Psychosom Med 2004; 66(5): 714-19.
Park J, Oremus M. Review of cardiovascular disease primary prevention interventions in LMICs. J Epidemiol Community Health 2014; 69(1): A1.3-A2.
Pandey KR, Meltzer DO. Financial burden and impoverishment due to cardiovascular medications in LMICs: an illustration from India. PLoS One 2016; 11(5): e0155293.
Otorkpa O, Otorkpa C, Adebola O, Emmanuel S, Adamu A, Olaniyan O, et al. From policy to practice: A review of Africa's public health policy. Cent Afr J Public Health 2024; 10(2): 90-9.
Ormel J. Prognostic association of depression after MI with mortality and cardiovascular events: A meta-analysis [Internet] 2015 [cited 2025 May 21]. Available from: http://intl.psychosomaticmedicine.org/content/66/6/814.full.pdf
Ocsovszky Z, Ehrenberger B, Berenyi B, Assabiny A, Otohal J, Martos T, et al. Positive cardiovascular health: a longitudinal investigation. Front Public Health 2024; 12: 1400849.
Nurrahma E, Widyadhana ANRA, Saraswati AL, Anugraheni A, Prasetyatama MJ, Huriyati E. Empowering family awareness of cardiovascular disease in Sleman Regency. J Pengabdian Kpd Masyarakat 2021; 7(2): 137.
Nicklaus Children's Hospital. New anaesthesia offering helps cardiac patients recover faster and with less pain [Internet]. [cited 2025 May 21]. Available from: https://www.nicklauschildrens.org/news-and-events/video-center/new-anesthesia-offering-helps-cardiac-patients-rec?lang=en
Nehra D, Sharma N, Kumar P, Nehra S. Efficacy of MBSR program in treating Depression, Anxiety and Perceived Stress in Coronary Heart Disease Patients. Indian J Posit Psychol 2012; 3: 91-5.
National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) | National AYUSH Mission (NAM) [Internet]. [cited 2025 May 21]. Available from: http://namayush.gov.in/content/national-programme-prevention-and-control-cancer-diabetes-cardiovascular-diseases-stroke
Nandy RR, Nandy K, Hébert ET, Businelle MS, Walters ST. Identifying behaviours Predicting early morning emotions by observing permanent supportive housing residents: an Ecological Momentary assessment. JMIR Ment Health 2018; 6(2): e10186.
Nambiar D, Bhaumik S, Pal A, Ved R. Assessing cardiovascular disease risk factor screening inequalities in India using Lot Quality Assurance Sampling. BMC Health Serv Res 2020; 20(1): 592.
Murphy B, Higgins R, Jackson A. Incidence and impacts of post-cardiac event mental health problems. Aust J Gen Pract 2023; 52(11): 781-6.
Moran A, Vedanthan R. Cardiovascular Disease Prevention in South Asia: Gathering the Evidence. Glob Heart 2013; 8(2): 139.
Montgomery RM, Boucher EM, Honomichl RD, Powell TA, Guyton SL, Bernecker SL, et al. The Effects of a Digital Mental Health Intervention in Adults With Cardiovascular Disease Risk Factors: Analysis of Real-World User Data. JMIR Ment Health 2021; 5(2): e32351.
Mohan V, Venkatraman JV, Pradeepa R. Epidemiology of Cardiovascular Disease in Type 2 Diabetes: the Indian scenario. J Diabetes Sci Technol 2010; 4(1): 158-70.
Middleton RA, Byrd EK. Psychosocial Factors and Hospital Readmission Status of Older Persons with Cardiovascular Disease. J Appl Rehabil Couns. 1996; 27(4): 3-10.
Mental Health and Cardiovascular Disease [Internet]. ReachMD. [cited 2025 May 21]. Available from: https://reachmd.com/programs/clinicians-roundtable/mental-health-and-cardiovascular-disease/458/
Mensah GA, Moran AE, Roth GA, Narula J. The global burden of cardiovascular diseases, 1990-2010. Glob Heart 2014; 9(1): 183.
Mazza M, Biondi-Zoccai G, Lisci FM, Brisi C, Sfratta G, Rossi S, et al. The brain-heart axis: an umbrella review on the impact of psychiatric disease on incidence, management, and outlook of cardiovascular disease. Life 2024; 14(8): 919.
Raič M. Depression and heart diseases: leading health problems. Med Acad Mostariensia 2017; 5(1-2): 52-9.
Mansur DP, Favarato D. Trends in mortality rate from cardiovascular disease in Brazil, 1980-2012 [Internet]. [cited 2025 May 21]. Available from: https://oasisbr.ibict.br/vufind/ Record/SBC1_dfc4c43e12932c99e63926841f5e8102/Details
Liu Z, Wang H, Yang Z, Lu Y, Wang J, Zou C. Mood instability may be causally associated with high risk of cardiovascular disease: a Mendelian randomization analysis. medRxiv [Preprint] 2023.
Liu X, Zhai B, Zhu X, Zheng Z, Yu J, Wang B, et al. Ameliorate cardiovascular condition through positive psychology and lifestyle intervention in China: study protocol of the ACCOMPLI-CH randomized controlled trial 2024.
Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature 2011; 473(7347): 317-25.
Li X, Zhou J, Wang M, Yang C, Sun G. Cardiovascular disease and depression: a narrative review. Front Cardiovasc Med 2023; 10.
Lange K, Lycett K, Ellul S, Saffery R, Mensah F, Carlin J, et al. Metabolic profiles of mental health in Australian children and adults: a cross-sectional analysis. Aust N Z J Psychiatry 2020; 54(9): 928-37.
Kwapong YA, Boakye E, Khan SS, Honigberg MC, Martin SS, Oyeka CP, et al. Association of depression and poor mental health with cardiovascular disease among young adults in the US. J Am Heart Assoc 2023; 12(3).
Kumar N, Mohammadnezhad M. Barriers to CVD risk management: physicians' perceptions. BMC Prim Care 2022; 23(1).
Kubzansky LD, Thurston RC. Emotional vitality and coronary heart disease. Arch Gen Psychiatry 2007; 64(12): 1393.
Kouidrat Y, Amad A, De Hert M. Emerging drugs for cardio-metabolic disorders in severe mental illness. Curr Pharm Des 2015; 21(23): 3317-24.
Kolev V, Manov E, Runev N, Stoimenov B, Onchev G, Pancheva R. Prevalence and severity of depression and anxiety in heart failure patients in Bulgaria. J IMAB 2023; 29(4): 5208-13.
Kokane A, Joshi R, Kotnis A, Chatterjee A, Yadav KK, Re-vadi G, et al. Risk factors for cardiovascular diseases using WHO STEPwise approach in Madhya Pradesh. Peer J 2020.
Khetan A, Zullo M, Rani A, Gupta R, Purushothaman R, Bajaj NS, et al. CHW-based CVD risk factor control in India: a cluster RCT. Glob Heart 2019; 14(4): 355.
Khanna AD, Duca LM, Kay JD, Shore J, Kelly SL, Crume T. Mental illness in congenital heart disease patients: Colorado surveillance data. Am J Cardiol 2019; 124(4): 618-26.
Khan N, Khan SIT, Joti S, Malik J, Faraz M, Ashraf A. Cardiovascular diseases and PTSD: an updated review. Cardiol Rev 2023.
Khan M, Gul R, Irshad E. Stress management effects on depression, anxiety, and stress in CVD patients. Biol Clin Sci Res J 2024; 2024(1): 1252.
Kgatla MN, Mothiba PTM, Malema RN, Makgahlela M, Sodi T, Mphekgwana PM, et al. Barriers to CVD behavioral interventions by CHWs in rural South Africa 2023.
Kempen BV. Evaluating strategies for the primary prevention of cardiovascular disease [Master's thesis]. Maastricht: Maastricht University; 2016.
Kemp AH, Arias JA, Fisher Z. Social ties, health and wellbeing: a literature review and model. In: Ibáñez A, Sedeño L, García AM, editors. Neuroscience and Social Science: The Missing Link 2018. Available from: https://core.ac.uk/download/96640803.pdf
Ke C, Gupta R, Shah BR, Stukel TA, Xavier D, Jha P. Association of hypertension and diabetes with ischemic heart disease and stroke mortality in India: The Million Death Study. Glob Heart 2021; 16(1): 69.
Kawas LH. Development of therapeutics targeting the hepatocyte growth factor (HGF)/MET system 2011.
Kala P, Hudakova N, Jurajda M, Kasparek T, Ustohal L, Parenica J, et al. Depression and anxiety after acute myocardial infarction treated by primary PCI. PLoS One 2016; 11(4): e0152367.
Kahl KG, Stapel B, Frieling H. Link between depression and cardiovascular diseases due to epigenomics and proteomics: focus on energy metabolism. Prog Neuropsychopharmacol Biol Psychiatry 2018; 89: 146-57.
Journal of IMAB. Site Map [Internet]. [cited 2025 May 21]. Available from: https://journal-imab-bg.org/sitemap.html
Jana A, Chattopadhyay A. Prevalence and potential determinants of chronic disease among elderly in India: rural-urban perspectives. PLoS One 2022; 17(3): e0264937.
Hussain S, Mir MB, Ahmad S. Mental health of cardiac patients in Gilgit, Pakistan: a cross-sectional study. Pak J Med Sci 2017. Available from: https://www.researchgate.net/ publication/320299207
Huebner M, Börnigen D, Deckert A, Holle R, Meisinger C, Müller-Nurasyid M, et al. Genetic variation and cardiovascular risk factors: a cohort study on migrants from the former Soviet Union and a native German population. Int J Environ Res Public Health 2021; 18(12): 6215.
Vidque. How long does it take to reduce inflammation on a plant-based diet? [Internet]. [cited 2025 May 21]. Available from: https://vidque.com/how-long-does-it-take-to-reduce-inflammation-on-a-plant-based-diet/
Hobbs FDR. Prevention of cardiovascular diseases. BMC Med 2015; 13(1).
Language for Life. Healthy mind and body [Internet]. [cited 2025 May 21]. Available from: https://languageforlife.com.au/ healthy-mind-and-body/
Hassan S, Heinkel S, Burton A, Blackburn R, McCloud T, Ross J, et al. A qualitative study exploring barriers and facilitators of implementing a CVD risk-reducing intervention for people with severe mental illness in primary care: the PRIMROSE trial. BMC Health Serv Res 2020; 20(1): 1-15.
Hamza M, Fatima G, Sana R, Ghafar S, Hamza A, Habib MT, et al. Impact of catechins, capsaicin, and gingerol in managing diabetes and reducing atherosclerosis risk. J Health Rehabil Res 2024; 4(1): 876-82.
Hammouda OT, Wu MY, Kaul V, Gierten J, Thumberger T, Wittbrodt J. In vivo identification and validation of novel potential predictors for human cardiovascular diseases. PLoS One 2021; 16(12): e0261572.
Haesebaert J. Considering health literacy in CVD management: a qualitative study of professionals' and patients' views. BMC Health Serv Res 2022; 22(1).
Gwak D, Ryu W, Schellingerhout D, Chung J, Kim H, Jeong S, et al. Effects of white matter hyperintensity burden on outcomes after ischemic stroke. Sci Rep 2024; 14(1).
Gurfein BT, Stamm AW, Bacchetti P, Dallman MF, Nadkarni NA, Milush JM, et al. The calm mouse: an animal model of stress reduction. Mol Med 2012; 18(4): 606-17.
Gupta R, Guptha S, Joshi R, Xavier D. Translating evidence into policy for CVD control in India. Health Res Policy Syst 2011; 9(1).
Gupta R, Wood DA. Primary prevention of ischaemic heart disease: populations, individuals, and professionals [Internet]. Lancet. [cited 2025 May 21]. Available from: https://nipc.ie/wp-content/uploads/2019/10/Lancet_Prev_1_ Gupta_Wood.pdf
Guimond A-J, Trudel-Fitzgerald C, Boehm JK, Qureshi F, Kubzansky LD. Psychological well-being and cardiometabolic disease. Health Psychol 2022; 41(1): 32-42.
Golovina K, Niemi R, Gutvilig M, Jokela M, Elovainio M, Hakulinen C. Mental disorders and first childbearing in young adults: a cohort study. BJOG 2025.
Goldie C. Cardiovascular risk in people with mental illness in Canada 2023.
Goldfarb M, De Hert M, Detraux J, Di Palo K, Munir H, Music S, et al. Severe mental illness and CVD. J Am Coll Cardiol 2022; 80(9): 918-33.
Giovancarli C, Malbos E, Baumstarck K, Parola N, Pélissier M, Lançon C, et al. VR cue exposure for tobacco relapse prevention: a trial protocol. Trials 2016; 17(1).
Gilani TA, Mir MS. Road traffic noise and coronary artery disease: a study in North India. Environ Sci Pollut Res 2021; 28(38): 53458-77
Elizondo JV, Khera R, Dudum R, Acquah I, Hyder AA, Andrieni JD, et al. Social determinants and financial toxicity in atherosclerotic CVD. Circulation 2020; 142.
Ekici B, Ercan EA, Cehreli S, Töre HF. Emotional status, quality of life, and CAD severity. Kardiol Pol 2014; 72(7): 617-23.
De Hert M, Detraux J, Vancampfort D. The intriguing relationship between coronary heart disease and mental disorders. Dialogues Clin Neurosci 2018; 20(1): 31-40.
Daumit GL, Dalcin A, Dickerson F, Miller ER, Evins AE, Cather C, et al. Effect of a comprehensive cardiovascular risk reduction intervention in persons with serious mental illness: a randomized clinical trial. JAMA Netw Open 2020; 3(6).
Dao DM, Cong HT, Nguyen TQ. Adolescent anxiety and depression about family, peer, and teacher interactions: a gender-sensitive approach. Multidiscip Sci J 2024; 7(4): 2025215.
Daniel CR, Prabhakaran D, Kapur K, Graubard BI, Devasenapathy N, Ramakrishnan L, et al. A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in India. Nutr J 2011; 10(1).
UQ Healthy Living. Chronic pain - where the body meets the brain [Internet]. [cited 2025 May 21]. Available from: https://www.uqhealthyliving.org.au/chronic-pain-where-the-body-meets-the-brain/
Chin AT, Rylance J, Makumbirofa S, Meffert S, Vu T, Clayton J, et al. Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study. Int J Tuberc Lung Dis 2019; 23(2): 203-11.
Chernoff RA, Messineo G, Kim S, Pizano DR, Korouri S, Danovitch I, et al. Psychosocial interventions for patients with heart failure: a systematic review and meta-analysis. Psychosom Med 2022; 84: 560-80.
Chaudhri K, Liu H, Joshi R. Barriers and facilitators for collaborative care in CVD: a qualitative study. Heart Lung Circ 2023; 32: S335.
Carter HE, Schofield D, Shrestha RN. Productivity costs of cardiovascular disease mortality across disease types and socioeconomic groups. Open Heart 2019; 6(1): 1-8.
Carmin CN, Ownby RL, Fontanella C, Steelesmith D, Binkley PF. Association of mental health treatment on outcomes in patients with heart failure and ischemic heart disease. medRxiv [Preprint] 2023.
Carmin CN, Ownby RL, Fontanella C, Steelesmith D, Binkley PF. Impact of mental health treatment on outcomes in patients with heart failure and ischemic heart disease. J Am Heart Assoc 2024; 13(7).
Nursing Center. Cardiovascular risk factors among prisoners: An integrative review [Internet]. [cited 2025 May 21]. Available from: https://www.nursingcenter.com/journalarticle? Article_ID=1514644
Buhay SRH, Butt A, Banguilan KK, Callejo CJ, Castillo ND, De Torres RK, et al. A different lens: Insights of non-nursing students in nursing education. World J Nurs Res 2024; 3(1): 50-63.
Bosanac P, Castle D. Psychoses and cardiovascular disease: the heart and mind of the matter. In: Alvarenga M, Byrne D, editors. Handbook of Psychocardiology. Singapore: Springer; 2016.
Boehm M, Nabel EG. The cell cycle and cardiovascular diseases. Prog Cell Cycle Res 2003; 5: 19-30. PMID: 14593697
Ble Castillo J, Morales Contreras J. Mental health disorders and coping strategies in healthcare workers during the COVID-19 pandemic. Int J Environ Res Public Health 2023; 20(5): 4230
Beaglehole R, Reddy S, Leeder SR. Poverty and human development: the global implications of cardiovascular disease. Circulation 2007; 116(17): 1871-3.
Banerjee K, Dwivedi LK. Burden assessment of infectious and cardiovascular diseases in India for the decade 2004-2014. Epidemiol Health 2016; e2016057.
Bagheri N, Gilmour B, McRae I, Konings P, Dawda P, Del Fante P, et al. Community cardiovascular disease risk: a spatial analysis. Prev Chronic Dis 2015; 12.